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Christiaan Klijn

2010
Varela, I., C. N. Klijn, P. J. Stephens, L. J. Mudie, L. Stebbings, D. Galappaththige, H. van der Gulden, E. Schut, S. Klarenbeek, P. J. Campbell, et al., "Somatic structural rearrangements in genetically engineered mouse mammary tumors.", Genome biology, vol. 11, issue 10, pp. R100, 2010 Oct 13. Abstract
Horlings, H. M., C. Lai, D. S. A. Nuyten, H. Halfwerk, P. Kristel, E. H. van Beers, S. A. Joosse, C. N. Klijn, P. M. Nederlof, M. J. T. Reinders, et al., "Integration of DNA copy number alterations and prognostic gene expression signatures in breast cancer patients.", Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 16, issue 2, pp. 651-63, 2010 Jan 15. Abstract
Klijn, C. N., J. J. Bot, D. J. Adams, M. J. T. Reinders, L. F. A. Wessels, and J. Jonkers, "Identification of networks of co-occurring, tumor-related DNA copy number changes using a genome-wide scoring approach.", PLoS computational biology, vol. 6, issue 1, pp. e1000631, 2010 Jan. Abstract
Holstege, H., E. H. van Beers, A. Velds, X. Liu, S. A. Joosse, S. Klarenbeek, E. Schut, R. M. Kerkhoven, C. N. Klijn, L. F. A. Wessels, et al., "Cross-species comparison of aCGH data from mouse and human BRCA1- and BRCA2-mutated breast cancers.", BMC cancer, vol. 10, pp. 455, 2010. Abstract
de Ronde, J. J., C. N. Klijn, A. Velds, H. Holstege, M. J. T. Reinders, J. Jonkers, and L. F. A. Wessels, "KC-SMARTR: An R package for detection of statistically significant aberrations in multi-experiment aCGH data.", BMC research notes, vol. 3, pp. 298, 2010. Abstract
Bruin, S. C., C. N. Klijn, G. - J. Liefers, L. M. Braaf, S. A. Joosse, E. H. van Beers, V. J. Verwaal, H. Morreau, L. F. A. Wessels, M. - L. F. van Velthuysen, et al., "Specific genomic aberrations in primary colorectal cancer are associated with liver metastases", BMC cancer, vol. 10, pp. 662, 2010. Abstract
2009
ten Hoeve, J. J., Prioritization of candidate cancer genes by combining mouse retroviral insertional mutagenesis data and human array comparative genomic hybridization data using a gene-centric approach, , vol. M.Sc.: Delft University of Technology, pp. 16 (26 suplement), June 19, 2009.  Download: Hoev09a.pdf (6.55 MB)
2008
Klijn, C. N., H. Holstege, J. de Ridder, X. Liu, M. J. T. Reinders, J. Jonkers, and L. F. A. Wessels, "Identification of cancer genes using a statistical framework for multi-experiment analysis of non-discretized array CGH data", Nucl. Acids Res., vol. 36, no. 6, pp. 2106-, 2008.
2007
van Vliet, M. H., C. N. Klijn, L. F. A. Wessels, and M. J. T. Reinders, "Module-Based Outcome Prediction Using Breast Cancer Compendia", PLoS ONE, vol. 2, no. 10: Public Library of Science, pp. e1047, Oct, 2007.
2006
Klijn, C. N., L. F. A. Wessels, J. Jonkers, and M. J. T. Reinders, Candidate cancer discovery using KC-SMART: a novel method for statistical multi-experiment aCGH data analysis, : Delft University of Technology, pp. 26, December 13, 2006.